Publications

I. Henry, D. Bernstein, M. Banet, Jane Mulligan, Steve Moulton, Greg Grudic, and Victor Convertino. Body-worn, non-invasive sensor for monitoring stroke volume, cardiac output and cardiovascular reserve. In Wireless Health 2011, La Jolla, CA, 2011.

Steven L. Moulton, Stephanie Haley-Andrews, and Jane Mulligan. Emerging technologies for pediatric and adult trauma care. Current Opinion in Pediatrics, 2010.


 

Noninvasive Medical Monitoring

People

Jane Mulligan
Steven Moulton
Greg Grudic

CipherSensor Display for integration with BMEYE NexFin Continuous BP Monitor

Abstract

Work in collaboration with Flashback Technologies and researchers from the US Army Institute for Surgical Research (USAISR) to extract features to detect and predict conditions such as blood loss, intercranial pressure and seizure from noninvasive measurements including ECG, ICG, TCD, EEG, SP02, and continous BP. We have integrated the CiperSensor with the BMEYE Nexfin continuous blood pressure monitor. We are currently working with Sotera Wireless on hardware and software integration of our algorithms with their ViSi device.

Researchers at USAISR study hypovolemia using Lower Body Negative Pressure (LBNP) to bring human subjects to the point of cardiovascular collapse. LBNP (see image below) applies increasing levels of negative pressure to the lower extremities over time pulling blood away from the heart and lungs. Noninvasive physiologic signals are measured at the same time to determine which sensors are effective predictors of blood loss.

We analyze the subject LBNP and sensor dataset to identify patterns and attributes of the signals which best facilitate prediction of blood loss and physiologic reserve, with the goal of building noninvasive sensors for blood loss which can be easily deployed in a combat casualty setting.

Subject at USAISR during Ciphersensor LBNP experiment Plot of ground truth and predicted LBNP
 
 
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