I. Henry, D. Bernstein, M. Banet, Jane Mulligan, Steve Moulton,
Greg Grudic, and Victor Convertino. Body-worn, non-invasive sensor
for monitoring stroke volume, cardiac output and cardiovascular
reserve. In Wireless Health 2011, La Jolla, CA, 2011.
Steven L. Moulton, Stephanie Haley-Andrews, and Jane
Mulligan. Emerging technologies for pediatric and adult trauma
care. Current Opinion in Pediatrics, 2010.
Work in collaboration with
Flashback Technologies and researchers from the US Army Institute
for Surgical Research (USAISR) to extract features to detect and
predict conditions such as blood loss, intercranial pressure and
seizure from noninvasive measurements including ECG, ICG, TCD, EEG,
SP02, and continous BP. We have integrated the CiperSensor
with the BMEYE Nexfin continuous
blood pressure monitor. We are currently working with Sotera Wireless on
hardware and software integration of our algorithms with their ViSi
device.
Researchers at USAISR study hypovolemia using Lower Body Negative
Pressure (LBNP) to bring human subjects to the point of cardiovascular
collapse. LBNP (see image below) applies increasing levels of negative
pressure to the lower extremities over time pulling blood away from
the heart and lungs. Noninvasive physiologic signals are measured at
the same time to determine which sensors are effective predictors of
blood loss.
We analyze the subject LBNP and sensor dataset to identify
patterns and attributes of the signals which best facilitate
prediction of blood loss and physiologic reserve, with the goal of
building noninvasive sensors for blood loss which can be easily
deployed in a combat casualty setting.